Michael D. Corbett, Ph.D.
Independent Consultant in Chemical Toxicology

 

PUBLICATIONS ( 67 Peer Reviewed, chronological order)

E.E. Smissman, M.D. Corbett, N.A. Jenny and O. Kristiansen, "Mechanism of the transformation of 2,4-dihydroxy-1,4-benzoxazin-3-ones and 2-hydroxy-2-methyl-4-methoxy-1,4-benzoxazin-3-one to 2-benzoxazolinone", J. Organic Chemistry., 37: 1700-1704 (1972).

E.E. Smissman and M.D. Corbett, "The synthesis of 4-acylamido-1,4-benzoxazine-2,3-diones and 4-(p-toluenesulfonamido)-1,4-benzoxazine- 2,3-dione", J. Organic Chemistry, 37: 1704-1707 (1972).

E.E. Smissman and M.D. Corbett, "A facile method for N-acylation of ring activated phenylhydroxylamines", J. Organic Chemistry, 37: 1847-1849 (1972).

E.E. Smissman, M.D. Corbett, S. El-Antably and K.C. Kroboth, "Anomalous ether formation in attempts to transesterify oxalate esters with phenoxides", J. Organic Chemistry, 37: 3944-3945 (1972).

M.D. Corbett, "Hydroxamic acids from the reaction of active acetaldehyde with aromatic nitroso compounds",Bioorganic Chemistry, 3: 361-365 (1974).

M.D. Corbett and S. Billets, "Characterization of poison oak urushiol", J. Pharmaceutical Sciences, 64: 1715-1718 (1975).

M.D. Corbett, J.E. Cahoy and B.R. Chipko, "Conversion of nitrosobenzene to N-phenylacetohydroxamic acid by yeast pyruvate decarboxylase", J. National Cancer Institute, 55: 1247-1248 (1975).

M.D. Corbett and B.R. Chipko, "N-Phenylglycolhydroxamate production by the action of transketolase on nitrosobenzene", Biochemical J., 165: 263-267 (1977).

S. Billets, J.C. Craig, M.D. Corbett and J.F. Vickery, "Component analysis of the urushiol content of poison ivy (T. radicans) and poison oak (T. diversilobum)", Phytochemistry, 15: 533-535 (1976).

M.D. Corbett, W.P. Duncan, B.R. Chipko and J.E. Cahoy, "Biosynthetic preparation of diethylstilbestrol monoglucuronide-(glucuronyl-U-14C), J. Labelled Compounds Radiopharmaceuticals, 14: 169-174 (1978).

M.D. Corbett, B.R. Chipko and J.H. Paul, "The production of hydroxamic acid metabolites of nitrosobenzene by Chlorella pyrenoidosa", J. Environmental Pathology Toxicology, 1: 259-266 (1978).

M.D. Corbett and B.R. Chipko, "Purification of hydroxamic acids by the use of ferric SP-Sephadex", J. Chromatography, 151: 379-383 (1978).

M.D. Corbett and B.R. Chipko, "Synthesis and antibiotic properties of chloramphenicol reduction products", Antimicrobial Agents Chemotherapy, 13: 193-198 (1978).

M.D. Corbett and B.R. Chipko, "Synthesis of N-aryl-N-glycolhydroxamic acids: non-microsomal metabolites of nitroso aromatics", Experientia, 34: 1125-1126 (1978).

M.D. Corbett, B.R. Chipko and D.G. Baden, "Chloroperoxidase-catalyzed oxidation of 4-chloroaniline to 4-chloronitrosobenzene", Biochemical J., 175: 353-360 (1978).

M.D. Corbett, D.G. Baden and B.R. Chipko, "Arylamine oxidation by chloroperoxidase", Bioorganic Chemistry, 8: 91-95 (1979).

M.D. Corbett, D.G. Baden and B.R. Chipko, "The non-microsomal production of N-(4-chlorophenyl)glycolhydroxamic acid from 4-chloronitrosobenzene by rat liver homogenates", Bioorganic Chemistry, 8: 227-235 (1979).

M.D. Corbett and B.R. Chipko, "Peroxidase activity in the sponge, Iotrochota birotulata", Experientia, 35: 718-719 (1979).

M.D. Corbett and B.R. Chipko, "Chloroperoxidase-catalyzed oxidation of N-methyl-4-chloroaniline", Experientia, 35: 1150-1151 (1979).

M.D. Corbett and B.R. Chipko, "Quantitative determination of N-arylaceto and N-arylglycolhydroxamic acids in biochemical reaction mixtures", Analytical Biochemistry, 98: 169-177 (1979).

M.D. Corbett and B.R. Chipko, "Peroxide oxidation of indole to oxindole by chloroperoxidase catalysis", Biochemical J., 183: 269-276 (1979).

D.G. Baden and M.D. Corbett, "Peroxidases produced by the marine sponge, Iotrochota birotulata", Comparative Biochemistry Physiology, 64: 279-284 (1979).

T.L. Pazdernik and M.D. Corbett, "Role of chloramphenicol reduction products on hemopoietic precursor cells in vitro", Pharmacology, 19: 191-195 (1979).

T.L. Pazdernik and M.D. Corbett, "Role of chloramphenicol reduction products in aplastic anemia", Pharmacology, 20: 87-94 (1980).

D.G. Baden and M.D. Corbett, "Bromoperoxidases from Penicillus capatatus, P. lamourouxii and Rhipocephalus phoenix, Biochemical J., 187: 205-211 (1980).

M.D. Corbett, B.R. Chipko and A.O. Batchelor, "The action of chloride peroxidase on 4-chloroaniline: N-oxidation and halogenation", Biochemical J., 187: 893-903 (1980).

D.G. Baden, M.D. Corbett and B.R. Chipko, "Competition by 4-chloronitrosobenzene for the active glycolaldehyde intermediate of transketolase", Bioorganic Chemistry, 9: 231-237 (1980).

M.D. Corbett and B.R. Corbett, "The reaction of nitroso aromatics with glyoxylic acid: a new path to hydroxamic acids", J. Organic Chemistry, 45: 2834-2838 (1980).

A.A. Yunis, A.M. Miller, Z. Salem, M.D. Corbett and G.K. Arimura, "Nitroso-chloramphenicol: possible mediator in chloramphenicol-induced aplastic anemia", J. Laboratory Clinical Medicine, 96: 36-46 (1980).

M.D. Corbett and B.R. Chipko, "Comparative aspects of hydroxamic acid production by thiamine-dependent enzymes", Bioorganic Chemistry, 9: 273-287 (1980).

M.D. Corbett and B.R. Corbett, "Metabolism of 4-chloronitrobenzene by the yeast Rhodosporidium sp.", Applied Environmental Microbiology, 41: 942-949 (1981).

M.D. Corbett and B.R. Corbett, "Reductive formylation of N,N-dimethyl-p-nitrosoaniline by glyoxylic acid. Evidence for a hydroxamic acid intermediate", J. Organic Chemistry, 46: 466-468 (1981).

M.D. Corbett, B.R. Corbett and D.R. Doerge, "Hydroxamic acid production and active-site induced Bamberger Rearrangement from the action of -ketoglutarate dehydrogenase on 4-chloronitrosobenzene", J. Chemical Society Perkin Transactions I, 345-350 (1982).

J.K. Baker, L.A. Cates, M.D. Corbett, J.W. Huber and D.L. Lattin, "Laboratory to laboratory reproducibility of high performance liquid chromatographic retention indicies", J. Liquid Chromatography, 5: 829-839 (1982).

M.D. Corbett and B.R. Corbett, "Enzymic generation of N-[4-(dimethylamino)phenyl]acetohydroxamic acid by the action of pyruvate decarboxylase on 4-(dimethylamino)nitrosobenzene", Bioorganic Chemistry, 11: 328-337 (1982).

M.D. Corbett and B.R. Corbett, "The generality of the nitroso-glyoxylate reaction: Conversion of p-nitronitrosobenzene to the hydroxamic acid", Experientia, 38: 1310-1311 (1982).

D.R. Doerge and M.D. Corbett, "Unsaturated fatty acid-dependent oxidation of epinephrine in homogenates of the gorgonian, Pseudoplexaura porosa", Chemico-Biological Interactions, 42: 117-126 (1982).

D.R. Doerge and M.D. Corbett, "An arachidonic acid-specific lipoxygenase from the gorgonian coral Pseudoplexaura porosa", Experientia, 38: 901-902 (1982).

M.D. Corbett, D.R. Doerge and B.R. Corbett, "Hydroxamic acid production by -ketoglutarate dehydrogenase. II. Evidence for an electrophilic reaction intermediate at the enzyme active site", J. Chemical Society Perkin Transactions I, 765-769 (1983).

M.D. Corbett and B.R. Corbett, "Enzymatic preparation of [U-14C]-4-chloronitrosobenzene", Experientia, 39: 487-488 (1983).

M.D. Corbett and B.R. Corbett, "Arylamine N-oxidation by the microsomal fraction of germinated pea seeds, Pisum sativum", J. Agriculture Food Chemistry, 31: 1276-1282 (1983).

M.D. Corbett, C.I. Wei, S. Fernando and B.R. Corbett, "The synthesis and mutagenicity of the N-formyl analog of N-hydroxyphenacetin", Carcinogenesis, 4: 1615-1617 (1983).

D.R. Doerge and M.D. Corbett, "Oxidation of organosulfur compounds by the microsomal fraction of germinating pea seeds (Pisum sativum)", Biochemical Biophysical Research Communications, 121: 1001-1005 (1984).

D.R. Doerge and M.D. Corbett, " Hydroperoxyflavin-mediated oxidations of organosulfur compounds: model studies for the flavin monooxygenase", Molecular Pharmacology., 26: 348-352 (1984).

D.R. Doerge and M.D. Corbett, "Primary arylamine oxidation by a flavinhydroperoxide. A study of the basis for the substrate specificity of the flavoprotein monooxygenase", Biochemical Pharmacology, 33: 3615-3619 (1984).

D.R. Doerge and M.D. Corbett, "The action of -ketoglutarate dehydrogenase on 4-chloronitrosobenzene: evidence for species-dependent differences in active site properties", Comparative Biochemistry Physiology, 80C: 161-165 (1985).

J.J. Johnston and M.D. Corbett, "The effects of temperature, salinity, and a simulated tidal cycle on the toxicity of fenitrothion to Callinectes sapidus", Comparative Biochemistry Physiology, 80C: 145-149 (1985).

C.I. Wei, M.D. Cohen, D.D. Swartz, S.Y. Fernando and M.D. Corbett, "Mutagenicity of some monoaromatic hydroxamic acids", Toxicology Letters, 24: 111-116 (1985).

M.D. Corbett, C. Wei and B.R. Corbett, "Nitroreductase-dependent mutagenicity of p-nitrophenylhydroxylamine and its N-acetyl and N-formyl hydroxamic acids", Carcinogenesis, 6: 727-732 (1985).

M.D. Corbett and B.R. Corbett, "Enzymatic N-oxidation of 4-nitroaniline", Biochemical Archives, 1: 115-120 (1985).

M.D. Corbett and B.R. Corbett, "Effect of ring substituents on the transketolase-catalyzed conversion of nitroso aromatics to hydroxamic acids", Biochemical Pharmacology, 35: 3613-3621 (1986).

J.J. Johnston and M.D. Corbett, "The uptake and in vivo metabolism of the organophosphate insecticide, fenitrothion, by the blue crab, Callinectes sapidus", Toxicology Applied Pharmacology, 85: 181-188 (1986).

J.J. Johnston and M.D. Corbett, "The effects of salinity and temperature on the in vitro metabolism of the organophosphorus insecticide, fenitrothion, by the blue crab, Callinectes sapidus", Pesticide Biochemistry Physiology, 26: 193-201 (1986).

M.D. Corbett, C.I. Wei, J.J. Johnston, P.F. Chang and B.R. Corbett, "Mutagenicity of the C-nitroso analog of fenitrothion", Toxicology Letters, 35: 201-207 (1987).

M.D. Corbett and B.R. Corbett, "HRP-Catalyzed bioactivation of carcinogenic hydroxamic acids. The greater reactivity of glycolyl versus acetyl derived hydroxamic acids", Chemico-Biological Interactions, 63: 249-264 (1987).

L.O. Lim, B.R. Corbett and M.D. Corbett, "Irreversible inhibition of the cytosolic metabolism of N-hydroxy-2-acetylaminofluorene by its glycolyl analog", Cancer Letters, 37: 205-211 (1987).

M.D. Corbett, L.O. Lim, B.R. Corbett, J.J. Johnston and P. Wiebkin, "Covalent binding of N-hydroxy-2-acetylaminofluorene and N-hydroxy-2-glycolylaminofluorene to rat hepatocyte DNA: In vitro and cell-suspension studies", Chemical Research Toxicology, 1: 41-46 (1988).

M.D. Corbett and B.R. Corbett, "N-Glycolyl hydroxamic acids: an improved synthetic method and the in-situ generation and intramolecular rearrangement of N-acetoxy-N-glycolyl-2-aminofluorene". Chemical Research Toxicology, 1: 222-227, (1988).

M.D. Corbett and B.R. Corbett, "Nucleic acid binding of arylamines during the respiratory burst of human granulocytes", Chemical Research Toxicology, 1: 356-363 (1988).

M.D. Corbett, B.R. Corbett, M.-H. Hannothiaux and S.J. Quintana, "The metabolic activation and nucleic acid binding of acetaminophen and related arylamine substrates by the respiratory burst of human granulocytes", Chemical Research Toxicology, 2: 260-266 (1989).

M.D. Corbett, B.R. Corbett, S.J. Quintana, M.-H. Hannothiaux and C.I. Wei, "Microsomal N-hydroxylation of the glycolamide, 2-(glycolamino)fluorene to give the glycolylhydroxamic acid. A new xenobiotic reaction", Chemical Research Toxicology, 3: 296-300 (1990).

P. Kovacic, M.A. Kassel, B.A. Feinberg, M.D. Corbett and R.A. McClelland, "Reduction potentials in relation to physiological activities of benzenoid and heterocyclic nitroso compounds: comparison with the nitro precursors", Bioorganic Chemistry 18: 265-275 (1990).

M.D. Corbett, M.-H. Hannothiaux and B.R. Corbett, "A comparison of the HL-60 cell line and human granulocytes to effect the bioactivation of arylamines and related xenobiotics. The binding of 2-aminofluorene to nucleic acids as the result of the respiratory burst", Chemico-Biological Interactions, 78: 33-54 (1991).

D.R. Doerge and M.D. Corbett, "Peroxygenation mechanism for chloroperoxidase-catalyzed N-oxidation of arylamines", Chemical Research Toxicology, 4: 556-560 (1991).

M.D. Corbett, B.R. Corbett, M.-H. Hannothiaux and S.J. Quintana, "The covalent binding of acetaminophen to cellular nucleic acids as the result of the respiratory burst of neutrophils derived from the HL-60 cell line", Toxicology Applied Pharmacology, 113: 80-86 (1992).

M.D. Corbett and B.R. Corbett, "Studies on the nitroso-glyoxylate reaction. Relative hydroxamic acid production by glyoxylate, pyruvate and formaldehyde in reactions with 4-nitrosobiphenyl", Chemical Research Toxicology, 6: 82-90 (1993).

M.D. Corbett and B.R. Corbett, "Human granulocyte mediated activation of aromatic amines", Polycyclic Aromatic Compounds, 7: 51-58 (1994).

OTHER PUBLICATIONS    ( 8 Reviews, Book Chapters and Full Proceedings, in chronological order)

A.A. Yunis, A.M. Miller, M.D. Corbett and Z. Salem, "On the mechanism of aplastic anemia from chloramphenicol", Proceedings from the Conference on Aplastic Anemia: Stem Cell Disease, NIH Publication No. NIH-81-1008, 1981, pp. 237-253.

M.D. Corbett and B.R. Corbett, "Reaction of nitroso aromatics with glyoxylic acid", In: (H. Kehl, Ed.)Chemistry and Biology of Hydroxamic Acids. Karger, New York, 1982, pp. 37-42.

M.D. Corbett and B.R. Corbett, "Hydroxamic acid production mediated by thiamine-dependent enzymes", In: (H. Kehl, Ed.) Chemistry and Biology of Hydroxamic Acids. Karger, New York, 1982, pp. 160-164.

M.D. Corbett and B.R. Corbett, "The reactions of C-nitroso aromatics with -Oxo acids", In: (J.W. Gorrod and L.A. Damani, Eds.) Biological Oxidation of Nitrogen in Organic Molecules. Ellis Horwood, Ltd. Chichester, 1985 pp. 400-408.

D. R. Doerge and M.D. Corbett, "Oxygenation of primary arylamines by a hydroperoxyflavin: Model studies for the flavoprotein monooxygenase", In: (J.W. Gorrod and L.A. Damani, Eds.) Biological Oxidation of Nitrogen in Organic Molecules. Ellis Horwood, Ltd., Chichester, 1985, pp. 107-114.

M.D. Corbett and B.R. Corbett, "Biochemical studies on the putative nitroso metabolite of chloramphenicol: A new model for the cause of aplastic anemia". In: (P.C. Howard, S.S. Hecht and F.A. Beland, Eds.) Nitroarenes: Occurrence, Metabolism and Biological Impact. Plenum Press, New York, 1990, pp. 245-255.

M.D. Corbett and B.R. Corbett, "Bioactivation of xenobiotics by the respiratory burst of human granulocytes", In: (M.T. Moslen and C.V. Smith, Eds.) Free Radical Mechanisms of Tissue Injury, CRC Press, Boca Raton, 1992, pp. 143-151.

M.D. Corbett and B.R. Corbett, "Bioorganic chemistry of the arylhydroxylamine and nitrosoarene functional groups", In: (J.C. Spain, Ed.) Biodegradation of Nitroaromatic Compounds. Plenum Press, New York ,1995, pp. 151-182.


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